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[[Category:ヘルペスウイルス]]
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</style>
</head>
<body>
<p class="p1"><br></p>
<table cellspacing="0" cellpadding="0" class="t1">
<tbody>
<tr>
<td valign="middle" class="td1">
<p class="p2"><span class="s1"><b>病名</b></span></p>
</td>
<td valign="middle" class="td2">
<p class="p2"><span class="s1"><b>原因</b></span></p>
</td>
<td valign="middle" class="td3">
<p class="p2"><span class="s1"><b>伝播・疫学</b></span></p>
</td>
<td valign="middle" class="td4">
<p class="p2"><span class="s1"><b>症状（臨床・病理）</b></span></p>
</td>
<td valign="middle" class="td5">
<p class="p2"><span class="s1"><b>診断・類症鑑別</b></span></p>
</td>
<td valign="middle" class="td6">
<p class="p2"><span class="s1"><b>予防・治療</b></span></p>
</td>
<td valign="middle" class="td7">
<p class="p2"><span class="s1"><b>重要事項</b></span></p>
</td>
<td valign="middle" class="td8">
<p class="p2"><span class="s1"><b>その他メモ</b></span></p>
</td>
</tr>
<tr>
<td rowspan="3" valign="middle" class="td9">
<p class="p2"><span class="s1"><b>和名：</b></span></p>
<p class="p2"><span class="s1"><b>犬ヘルペスウイルス感染症</b></span></p>
</td>
<td rowspan="3" valign="top" class="td10">
<p class="p3"><span class="s1">和名：</span></p>
<p class="p3"><span class="s1">犬ヘルペスウイルス１</span></p>
</td>
<td valign="top" class="td11">
<p class="p3"><span class="s1">感染様式：</span></p>
<p class="p3"><span class="s1">感染犬の口・鼻・腟分泌物中のウイルスが経口・経鼻・経腟感染。</span></p>
<p class="p3"><span class="s1">胎盤・産道感染（死産、生後直死）</span></p>
<p class="p3"><span class="s1">不顕性感染犬での（三叉神経節）神経節への潜伏感染あり。</span></p>
</td>
<td valign="top" class="td12">
<p class="p3"><span class="s1">臨床：</span></p>
<p class="p4"><span class="s2">＜</span><span class="s1">移行抗体をもたない新生子犬</span><span class="s2">＞</span></p>
<p class="p3"><span class="s1">１カ月齢未満の子犬にのみ重篤な症状。</span></p>
<p class="p3"><span class="s1">移行抗体のない新生犬に感染すると黄緑色の軟便に始まり，</span></p>
<p class="p3"><span class="s1">呼吸困難，</span></p>
<p class="p3"><span class="s1">腹痛，</span></p>
<p class="p3"><span class="s1">食欲不振。</span></p>
<p class="p3"><span class="s1">嘔吐</span></p>
</td>
<td rowspan="2" valign="top" class="td13">
<p class="p3"><span class="s1">診断：</span></p>
<p class="p3"><span class="s1">ウイルス分離：病変部から採材し犬腎で培養。CPE→FA</span></p>
<p class="p3"><span class="s1">抗体検出：HI,NT,ELISA</span></p>
</td>
<td rowspan="3" valign="top" class="td14">
<p class="p3"><span class="s1">予防：</span></p>
<p class="p3"><span class="s1">日本にはワクチンはなし。衛生管理が重要。</span></p>
</td>
<td rowspan="4" valign="top" class="td15">
<p class="p3"><span class="s1">１．新生犬の全身性出血性感染症</span></p>
<p class="p3"><span class="s1">２．新生犬での死亡率は高いが4週齢以上の犬では呼吸器疾患や生殖器疾患を起こすが，重篤ではない</span></p>
</td>
<td rowspan="4" valign="top" class="td16">
<p class="p3"><span class="s1">ヘルペスウイルスなので三叉神経に潜伏感染</span></p>
<p class="p3"><span class="s1">Kennel coughの一因</span></p>
<p class="p3"><span class="s1">猫ヘルペスウイルス１と抗原交差あり</span></p>
<p class="p3"><span class="s1">潜伏期：３～５日程度</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td17">
<p class="p3"><span class="s1">世界：</span></p>
<p class="p3"><span class="s1">世界中に広く分布</span></p>
</td>
<td valign="top" class="td18">
<p class="p3"><span class="s1">予後：</span></p>
<p class="p3"><span class="s1">生犬での経過は短く，症状が出て１～２日以内に大半は死亡。</span></p>
<p class="p3"><span class="s1">４週齢以上の子犬では軽度の鼻炎，咽頭炎，膣炎を引き起こすのみ。</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td19">
<p class="p3"><span class="s1">日本：</span></p>
<p class="p3"><span class="s1">あり</span></p>
</td>
<td valign="top" class="td20">
<p class="p3"><span class="s1">子犬：</span></p>
<p class="p3"><span class="s1">くしゃみ・水様性鼻汁</span></p>
</td>
<td valign="top" class="td21">
<p class="p3"><span class="s1">血清学的診断：</span></p>
</td>
</tr>
<tr>
<td valign="middle" class="td22">
<p class="p2"><span class="s1"><b>英名：</b></span></p>
<p class="p2"><span class="s1"><b>canine herpesvirus infection</b></span></p>
</td>
<td valign="top" class="td23">
<p class="p3"><span class="s1">英名：</span></p>
<p class="p3"><span class="s1">Herpesviridae</span></p>
<p class="p3"><span class="s1">Alphaherpesvirinae</span></p>
<p class="p3"><span class="s1">Varicellovirus</span></p>
</td>
<td valign="top" class="td24">
<p class="p3"><span class="s1">宿主：</span></p>
<p class="p3"><span class="s1">犬科動物</span></p>
</td>
<td valign="top" class="td25">
<p class="p3"><span class="s1">病理：</span></p>
<p class="p3"><span class="s1">腎臓、肝臓、肺の点状出血と巣状壊死</span></p>
<p class="p4"><span class="s2">死亡した犬の</span><span class="s1">腎・肺・肝・腸管などに斑状出血と巣状壊死</span><span class="s2">。</span></p>
<p class="p3"><span class="s1">壊死巣周辺の細胞に好酸性または好塩基性核内封入体</span></p>
</td>
<td valign="top" class="td26">
<p class="p3"><span class="s1">類症鑑別：</span></p>
</td>
<td valign="top" class="td27">
<p class="p3"><span class="s1">治療：</span></p>
<p class="p3"><span class="s1">治療法はない。対処療法のみ。（不確定情報：インターフェロン療法で予防可能？しかし現実的ではない）</span></p>
</td>
</tr>
</tbody>
</table>
<p class="p1"><br></p>
</body>
</html>
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</style>
</head>
<body>
<p class="p1"><br></p>
<table cellspacing="0" cellpadding="0" class="t1">
<tbody>
<tr>
<td valign="middle" class="td1">
<p class="p2"><span class="s1"><b>病名</b></span></p>
</td>
<td valign="middle" class="td2">
<p class="p2"><span class="s1"><b>原因</b></span></p>
</td>
<td valign="middle" class="td3">
<p class="p2"><span class="s1"><b>伝播・疫学</b></span></p>
</td>
<td valign="middle" class="td4">
<p class="p2"><span class="s1"><b>症状（臨床・病理）</b></span></p>
</td>
<td valign="middle" class="td5">
<p class="p2"><span class="s1"><b>診断・類症鑑別</b></span></p>
</td>
<td valign="middle" class="td6">
<p class="p2"><span class="s1"><b>予防・治療</b></span></p>
</td>
<td valign="middle" class="td7">
<p class="p2"><span class="s1"><b>重要事項</b></span></p>
</td>
<td valign="middle" class="td8">
<p class="p2"><span class="s1"><b>その他メモ</b></span></p>
</td>
</tr>
<tr>
<td rowspan="3" valign="middle" class="td9">
<p class="p2"><span class="s1"><b>和名：</b></span></p>
<p class="p2"><span class="s1"><b>犬ヘルペスウイルス感染症</b></span></p>
</td>
<td rowspan="3" valign="top" class="td10">
<p class="p3"><span class="s1">和名：</span></p>
<p class="p3"><span class="s1">犬ヘルペスウイルス１</span></p>
</td>
<td valign="top" class="td11">
<p class="p3"><span class="s1">感染様式：</span></p>
<p class="p3"><span class="s1">感染犬の口・鼻・腟分泌物中のウイルスが経口・経鼻・経腟感染。</span></p>
<p class="p3"><span class="s1">胎盤・産道感染（死産、生後直死）</span></p>
<p class="p3"><span class="s1">不顕性感染犬での（三叉神経節）神経節への潜伏感染あり。</span></p>
</td>
<td valign="top" class="td12">
<p class="p3"><span class="s1">臨床：</span></p>
<p class="p4"><span class="s2">＜</span><span class="s1">移行抗体をもたない新生子犬</span><span class="s2">＞</span></p>
<p class="p3"><span class="s1">１カ月齢未満の子犬にのみ重篤な症状。</span></p>
<p class="p3"><span class="s1">移行抗体のない新生犬に感染すると黄緑色の軟便に始まり，</span></p>
<p class="p3"><span class="s1">呼吸困難，</span></p>
<p class="p3"><span class="s1">腹痛，</span></p>
<p class="p3"><span class="s1">食欲不振。</span></p>
<p class="p3"><span class="s1">嘔吐</span></p>
</td>
<td rowspan="2" valign="top" class="td13">
<p class="p3"><span class="s1">診断：</span></p>
<p class="p3"><span class="s1">ウイルス分離：病変部から採材し犬腎で培養。CPE→FA</span></p>
<p class="p3"><span class="s1">抗体検出：HI,NT,ELISA</span></p>
</td>
<td rowspan="3" valign="top" class="td14">
<p class="p3"><span class="s1">予防：</span></p>
<p class="p3"><span class="s1">日本にはワクチンはなし。衛生管理が重要。</span></p>
</td>
<td rowspan="4" valign="top" class="td15">
<p class="p3"><span class="s1">１．新生犬の全身性出血性感染症</span></p>
<p class="p3"><span class="s1">２．新生犬での死亡率は高いが4週齢以上の犬では呼吸器疾患や生殖器疾患を起こすが，重篤ではない</span></p>
</td>
<td rowspan="4" valign="top" class="td16">
<p class="p3"><span class="s1">ヘルペスウイルスなので三叉神経に潜伏感染</span></p>
<p class="p3"><span class="s1">Kennel coughの一因</span></p>
<p class="p3"><span class="s1">猫ヘルペスウイルス１と抗原交差あり</span></p>
<p class="p3"><span class="s1">潜伏期：３～５日程度</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td17">
<p class="p3"><span class="s1">世界：</span></p>
<p class="p3"><span class="s1">世界中に広く分布</span></p>
</td>
<td valign="top" class="td18">
<p class="p3"><span class="s1">予後：</span></p>
<p class="p3"><span class="s1">生犬での経過は短く，症状が出て１～２日以内に大半は死亡。</span></p>
<p class="p3"><span class="s1">４週齢以上の子犬では軽度の鼻炎，咽頭炎，膣炎を引き起こすのみ。</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td19">
<p class="p3"><span class="s1">日本：</span></p>
<p class="p3"><span class="s1">あり</span></p>
</td>
<td valign="top" class="td20">
<p class="p3"><span class="s1">子犬：</span></p>
<p class="p3"><span class="s1">くしゃみ・水様性鼻汁</span></p>
</td>
<td valign="top" class="td21">
<p class="p3"><span class="s1">血清学的診断：</span></p>
</td>
</tr>
<tr>
<td valign="middle" class="td22">
<p class="p2"><span class="s1"><b>英名：</b></span></p>
<p class="p2"><span class="s1"><b>canine herpesvirus infection</b></span></p>
</td>
<td valign="top" class="td23">
<p class="p3"><span class="s1">英名：</span></p>
<p class="p3"><span class="s1">Herpesviridae</span></p>
<p class="p3"><span class="s1">Alphaherpesvirinae</span></p>
<p class="p3"><span class="s1">Varicellovirus</span></p>
</td>
<td valign="top" class="td24">
<p class="p3"><span class="s1">宿主：</span></p>
<p class="p3"><span class="s1">犬科動物</span></p>
</td>
<td valign="top" class="td25">
<p class="p3"><span class="s1">病理：</span></p>
<p class="p3"><span class="s1">腎臓、肝臓、肺の点状出血と巣状壊死</span></p>
<p class="p4"><span class="s2">死亡した犬の</span><span class="s1">腎・肺・肝・腸管などに斑状出血と巣状壊死</span><span class="s2">。</span></p>
<p class="p3"><span class="s1">壊死巣周辺の細胞に好酸性または好塩基性核内封入体</span></p>
</td>
<td valign="top" class="td26">
<p class="p3"><span class="s1">類症鑑別：</span></p>
</td>
<td valign="top" class="td27">
<p class="p3"><span class="s1">治療：</span></p>
<p class="p3"><span class="s1">治療法はない。対処療法のみ。（不確定情報：インターフェロン療法で予防可能？しかし現実的ではない）</span></p>
</td>
</tr>
</tbody>
</table>
<p class="p1"><br></p>
</body>
</html>