北野成昭(キタノナルアキ) 作『獣医志Wiki』はクリエイティブ・コモンズ 表示 - 非営利 - 継承 4.0 国際 ライセンスで提供されています。
ページの作成:「<html> <head> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"> <meta http-equiv="Content-Style-Type" content="text/css"> <title></title> <meta...」
<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<meta http-equiv="Content-Style-Type" content="text/css">
<title></title>
<meta name="Generator" content="Cocoa HTML Writer">
<meta name="CocoaVersion" content="1343.16">
<style type="text/css">
p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; min-height: 14.0px}
p.p2 {margin: 0.0px 0.0px 0.0px 0.0px; text-align: center; font: 15.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p3 {margin: 0.0px 0.0px 0.0px 0.0px; text-align: center; font: 13.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p4 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p5 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; color: #ff2600; -webkit-text-stroke: #ff2600}
p.p6 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; color: #ea8500; -webkit-text-stroke: #ea8500}
p.p7 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; -webkit-text-stroke: #000000; min-height: 14.0px}
span.s1 {font-kerning: none}
span.s2 {font-kerning: none; color: #000000; -webkit-text-stroke: 0px #000000}
span.s3 {text-decoration: underline ; font-kerning: none}
span.s4 {font-kerning: none; color: #0433ff; -webkit-text-stroke: 0px #0433ff}
table.t1 {border-collapse: collapse}
td.td1 {width: 122.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td2 {width: 130.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td3 {width: 161.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td4 {width: 323.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td5 {width: 193.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td6 {width: 128.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td7 {width: 120.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td8 {width: 145.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td9 {width: 122.0px; height: 238.0px; background-color: #ff4580; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td10 {width: 132.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 5.0px; border-color: #e1c9a9 #000000 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td11 {width: 165.0px; height: 98.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td12 {width: 327.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td13 {width: 197.0px; height: 141.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td14 {width: 130.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 1.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td15 {width: 120.0px; height: 389.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td16 {width: 145.0px; height: 389.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td17 {width: 165.0px; height: 30.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td18 {width: 165.0px; height: 84.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td19 {width: 197.0px; height: 84.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td20 {width: 122.0px; height: 138.0px; background-color: #ff4580; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td21 {width: 132.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 5.0px; border-color: #e1c9a9 #000000 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td22 {width: 165.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td23 {width: 327.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td24 {width: 197.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td25 {width: 130.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 1.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
</style>
</head>
<body>
<p class="p1"><br></p>
<table cellspacing="0" cellpadding="0" class="t1">
<tbody>
<tr>
<td valign="middle" class="td1">
<p class="p2"><span class="s1"><b>病名</b></span></p>
</td>
<td valign="middle" class="td2">
<p class="p2"><span class="s1"><b>原因</b></span></p>
</td>
<td valign="middle" class="td3">
<p class="p2"><span class="s1"><b>伝播・疫学</b></span></p>
</td>
<td valign="middle" class="td4">
<p class="p2"><span class="s1"><b>症状（臨床・病理）</b></span></p>
</td>
<td valign="middle" class="td5">
<p class="p2"><span class="s1"><b>診断・類症鑑別</b></span></p>
</td>
<td valign="middle" class="td6">
<p class="p2"><span class="s1"><b>予防・治療</b></span></p>
</td>
<td valign="middle" class="td7">
<p class="p2"><span class="s1"><b>重要事項</b></span></p>
</td>
<td valign="middle" class="td8">
<p class="p2"><span class="s1"><b>その他メモ</b></span></p>
</td>
</tr>
<tr>
<td rowspan="3" valign="middle" class="td9">
<p class="p3"><span class="s1"><b>和名：</b></span></p>
<p class="p3"><span class="s1"><b>犬ジステンパー</b></span></p>
</td>
<td rowspan="3" valign="top" class="td10">
<p class="p4"><span class="s1">和名：</span></p>
<p class="p4"><span class="s1">犬ジステンパーウイルス</span></p>
</td>
<td valign="top" class="td11">
<p class="p4"><span class="s1">感染様式：</span></p>
<p class="p4"><span class="s1">直接接触，患犬の分泌物との接触や飛沫の吸入</span></p>
<p class="p4"><span class="s1">・尿中に長期間ウイルス排泄</span></p>
</td>
<td rowspan="3" valign="top" class="td12">
<p class="p4"><span class="s1">臨床：</span></p>
<p class="p4"><span class="s1">無症状から重篤なものまで多様。</span></p>
<p class="p5"><span class="s1">二峰性の発熱</span><span class="s2">，</span></p>
<p class="p4"><span class="s1">・白血球減少，</span></p>
<p class="p4"><span class="s1">・(水様性)鼻汁，くしゃみ，食欲減退，発疹(内股部)，</span></p>
<p class="p4"><span class="s1">・下痢，痩削，</span></p>
<p class="p4"><span class="s1">・脳炎など。</span></p>
<p class="p6"><span class="s2">・</span><span class="s1">足，鼻の角化(hyperkeratosis：硬蹠症：こうせきしょう)</span></p>
<p class="p4"><span class="s1">・二次感染により病状が悪化。</span></p>
</td>
<td rowspan="2" valign="top" class="td13">
<p class="p4"><span class="s1">診断：</span></p>
<p class="p4"><span class="s1"><b>ウイルス分離は困難</b>，鼻粘膜や結膜の塗抹標本での封入体や</span></p>
<p class="p4"><span class="s1"><b>ウイルス抗原の検出</b>，</span></p>
<p class="p4"><span class="s1">・急性期の結膜・扁桃・膀胱・膣・白血球層の塗抹を→蛍光抗体法orRT-PCR。</span></p>
</td>
<td rowspan="3" valign="top" class="td14">
<p class="p4"><span class="s1">予防：</span></p>
<p class="p4"><span class="s1">弱毒生ワクチンを接種する際，</span><span class="s3">移行抗体の有無に注意が必要</span></p>
</td>
<td rowspan="4" valign="top" class="td15">
<p class="p4"><span class="s1">きわめて伝染力が強い感染症で，弱毒生ワクチンで予防</span></p>
<p class="p4"><span class="s1">呼吸器，消化器，神経系を含む多様な病状</span></p>
<p class="p4"><span class="s1">間質性肺炎</span></p>
<p class="p4"><span class="s1">非化膿性脳炎</span></p>
<p class="p4"><span class="s1">脱髄性脳炎</span></p>
<p class="p4"><span class="s1">老犬脳炎</span></p>
<p class="p4"><span class="s1">硬蹠症<span class="Apple-converted-space"> </span></span></p>
<p class="p7"><br></p>
</td>
<td rowspan="4" valign="top" class="td16">
<p class="p4"><span class="s1">潜伏期：１週間以内から４週間</span></p>
<p class="p4"><span class="s1">予後：神経症状を示した場合の死亡率は高く，回復しても予後は不良。</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td17">
<p class="p4"><span class="s1">世界：</span></p>
<p class="p4"><span class="s1">世界中に広く分布</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td18">
<p class="p4"><span class="s1">日本：</span></p>
<p class="p4"><span class="s1">あり</span></p>
</td>
<td valign="top" class="td19">
<p class="p4"><span class="s1">血清学的診断：</span></p>
<p class="p4"><span class="s1">抗体の検出→</span></p>
<p class="p4"><span class="s1">・ペア血清による中和テスト，</span></p>
<p class="p4"><span class="s1">・蛍光抗体法，</span></p>
<p class="p4"><span class="s1">・酵素抗体法</span></p>
</td>
</tr>
<tr>
<td valign="middle" class="td20">
<p class="p3"><span class="s1"><b>英名：</b></span></p>
<p class="p3"><span class="s1"><b>canine distemper</b></span></p>
</td>
<td valign="top" class="td21">
<p class="p4"><span class="s1">英名：</span></p>
<p class="p4"><span class="s1">Paramyxoviridae, Paramyxovirinae, Morbillivirus</span></p>
</td>
<td valign="top" class="td22">
<p class="p4"><span class="s1">宿主：</span></p>
<p class="p4"><span class="s1">犬，キツネ，コヨーテ，タヌキ，イタチ，フェレット，ミンク，スカンク</span></p>
</td>
<td valign="top" class="td23">
<p class="p4"><span class="s1">病理：</span></p>
<p class="p5"><span class="s2">・</span><span class="s1">リンパ系組織と上皮組織に病変</span><span class="s2">。</span></p>
<p class="p4"><span class="s1">・胸腺の萎縮，リンパ球の脱落，</span></p>
<p class="p4"><span class="s1">・間質性およびカタル性肺炎。</span></p>
<p class="p4"><span class="s1">・エオジン好性の細胞質内および核内封入体(膀胱上皮，腎盂，グリア細胞，神経細胞，気管支上皮など)。</span></p>
<p class="p4"><span class="s1">・ウイルスが脳内に侵入してジステンパー脳炎→小脳脱髄病変。（→</span><span class="s4">LFB(ルクソール・ファーストブルー)染色で青</span><span class="s1">）</span></p>
</td>
<td valign="top" class="td24">
<p class="p4"><span class="s1">類症鑑別：</span></p>
</td>
<td valign="top" class="td25">
<p class="p4"><span class="s1">治療：</span></p>
<p class="p4"><span class="s1">二次感染を防ぐための抗生物質投与</span></p>
</td>
</tr>
</tbody>
</table>
<p class="p7"><br></p>
</body>
</html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<meta http-equiv="Content-Style-Type" content="text/css">
<title></title>
<meta name="Generator" content="Cocoa HTML Writer">
<meta name="CocoaVersion" content="1343.16">
<style type="text/css">
p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; min-height: 14.0px}
p.p2 {margin: 0.0px 0.0px 0.0px 0.0px; text-align: center; font: 15.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p3 {margin: 0.0px 0.0px 0.0px 0.0px; text-align: center; font: 13.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p4 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; -webkit-text-stroke: #000000}
p.p5 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; color: #ff2600; -webkit-text-stroke: #ff2600}
p.p6 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Hiragino Kaku Gothic ProN'; color: #ea8500; -webkit-text-stroke: #ea8500}
p.p7 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Helvetica; -webkit-text-stroke: #000000; min-height: 14.0px}
span.s1 {font-kerning: none}
span.s2 {font-kerning: none; color: #000000; -webkit-text-stroke: 0px #000000}
span.s3 {text-decoration: underline ; font-kerning: none}
span.s4 {font-kerning: none; color: #0433ff; -webkit-text-stroke: 0px #0433ff}
table.t1 {border-collapse: collapse}
td.td1 {width: 122.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td2 {width: 130.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td3 {width: 161.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td4 {width: 323.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td5 {width: 193.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td6 {width: 128.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td7 {width: 120.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td8 {width: 145.0px; height: 71.0px; background-color: #ff6847; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td9 {width: 122.0px; height: 238.0px; background-color: #ff4580; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td10 {width: 132.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 5.0px; border-color: #e1c9a9 #000000 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td11 {width: 165.0px; height: 98.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td12 {width: 327.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td13 {width: 197.0px; height: 141.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td14 {width: 130.0px; height: 238.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 1.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td15 {width: 120.0px; height: 389.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td16 {width: 145.0px; height: 389.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td17 {width: 165.0px; height: 30.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td18 {width: 165.0px; height: 84.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td19 {width: 197.0px; height: 84.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td20 {width: 122.0px; height: 138.0px; background-color: #ff4580; border-style: solid; border-width: 5.0px 5.0px 5.0px 5.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td21 {width: 132.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 5.0px; border-color: #e1c9a9 #000000 #e1c9a9 #e1c9a9; padding: 4.0px 4.0px 4.0px 4.0px}
td.td22 {width: 165.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td23 {width: 327.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td24 {width: 197.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 1.0px 5.0px 1.0px; border-color: #e1c9a9 #000000 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
td.td25 {width: 130.0px; height: 138.0px; background-color: #dbdece; border-style: solid; border-width: 5.0px 5.0px 5.0px 1.0px; border-color: #e1c9a9 #e1c9a9 #e1c9a9 #000000; padding: 4.0px 4.0px 4.0px 4.0px}
</style>
</head>
<body>
<p class="p1"><br></p>
<table cellspacing="0" cellpadding="0" class="t1">
<tbody>
<tr>
<td valign="middle" class="td1">
<p class="p2"><span class="s1"><b>病名</b></span></p>
</td>
<td valign="middle" class="td2">
<p class="p2"><span class="s1"><b>原因</b></span></p>
</td>
<td valign="middle" class="td3">
<p class="p2"><span class="s1"><b>伝播・疫学</b></span></p>
</td>
<td valign="middle" class="td4">
<p class="p2"><span class="s1"><b>症状（臨床・病理）</b></span></p>
</td>
<td valign="middle" class="td5">
<p class="p2"><span class="s1"><b>診断・類症鑑別</b></span></p>
</td>
<td valign="middle" class="td6">
<p class="p2"><span class="s1"><b>予防・治療</b></span></p>
</td>
<td valign="middle" class="td7">
<p class="p2"><span class="s1"><b>重要事項</b></span></p>
</td>
<td valign="middle" class="td8">
<p class="p2"><span class="s1"><b>その他メモ</b></span></p>
</td>
</tr>
<tr>
<td rowspan="3" valign="middle" class="td9">
<p class="p3"><span class="s1"><b>和名：</b></span></p>
<p class="p3"><span class="s1"><b>犬ジステンパー</b></span></p>
</td>
<td rowspan="3" valign="top" class="td10">
<p class="p4"><span class="s1">和名：</span></p>
<p class="p4"><span class="s1">犬ジステンパーウイルス</span></p>
</td>
<td valign="top" class="td11">
<p class="p4"><span class="s1">感染様式：</span></p>
<p class="p4"><span class="s1">直接接触，患犬の分泌物との接触や飛沫の吸入</span></p>
<p class="p4"><span class="s1">・尿中に長期間ウイルス排泄</span></p>
</td>
<td rowspan="3" valign="top" class="td12">
<p class="p4"><span class="s1">臨床：</span></p>
<p class="p4"><span class="s1">無症状から重篤なものまで多様。</span></p>
<p class="p5"><span class="s1">二峰性の発熱</span><span class="s2">，</span></p>
<p class="p4"><span class="s1">・白血球減少，</span></p>
<p class="p4"><span class="s1">・(水様性)鼻汁，くしゃみ，食欲減退，発疹(内股部)，</span></p>
<p class="p4"><span class="s1">・下痢，痩削，</span></p>
<p class="p4"><span class="s1">・脳炎など。</span></p>
<p class="p6"><span class="s2">・</span><span class="s1">足，鼻の角化(hyperkeratosis：硬蹠症：こうせきしょう)</span></p>
<p class="p4"><span class="s1">・二次感染により病状が悪化。</span></p>
</td>
<td rowspan="2" valign="top" class="td13">
<p class="p4"><span class="s1">診断：</span></p>
<p class="p4"><span class="s1"><b>ウイルス分離は困難</b>，鼻粘膜や結膜の塗抹標本での封入体や</span></p>
<p class="p4"><span class="s1"><b>ウイルス抗原の検出</b>，</span></p>
<p class="p4"><span class="s1">・急性期の結膜・扁桃・膀胱・膣・白血球層の塗抹を→蛍光抗体法orRT-PCR。</span></p>
</td>
<td rowspan="3" valign="top" class="td14">
<p class="p4"><span class="s1">予防：</span></p>
<p class="p4"><span class="s1">弱毒生ワクチンを接種する際，</span><span class="s3">移行抗体の有無に注意が必要</span></p>
</td>
<td rowspan="4" valign="top" class="td15">
<p class="p4"><span class="s1">きわめて伝染力が強い感染症で，弱毒生ワクチンで予防</span></p>
<p class="p4"><span class="s1">呼吸器，消化器，神経系を含む多様な病状</span></p>
<p class="p4"><span class="s1">間質性肺炎</span></p>
<p class="p4"><span class="s1">非化膿性脳炎</span></p>
<p class="p4"><span class="s1">脱髄性脳炎</span></p>
<p class="p4"><span class="s1">老犬脳炎</span></p>
<p class="p4"><span class="s1">硬蹠症<span class="Apple-converted-space"> </span></span></p>
<p class="p7"><br></p>
</td>
<td rowspan="4" valign="top" class="td16">
<p class="p4"><span class="s1">潜伏期：１週間以内から４週間</span></p>
<p class="p4"><span class="s1">予後：神経症状を示した場合の死亡率は高く，回復しても予後は不良。</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td17">
<p class="p4"><span class="s1">世界：</span></p>
<p class="p4"><span class="s1">世界中に広く分布</span></p>
</td>
</tr>
<tr>
<td valign="top" class="td18">
<p class="p4"><span class="s1">日本：</span></p>
<p class="p4"><span class="s1">あり</span></p>
</td>
<td valign="top" class="td19">
<p class="p4"><span class="s1">血清学的診断：</span></p>
<p class="p4"><span class="s1">抗体の検出→</span></p>
<p class="p4"><span class="s1">・ペア血清による中和テスト，</span></p>
<p class="p4"><span class="s1">・蛍光抗体法，</span></p>
<p class="p4"><span class="s1">・酵素抗体法</span></p>
</td>
</tr>
<tr>
<td valign="middle" class="td20">
<p class="p3"><span class="s1"><b>英名：</b></span></p>
<p class="p3"><span class="s1"><b>canine distemper</b></span></p>
</td>
<td valign="top" class="td21">
<p class="p4"><span class="s1">英名：</span></p>
<p class="p4"><span class="s1">Paramyxoviridae, Paramyxovirinae, Morbillivirus</span></p>
</td>
<td valign="top" class="td22">
<p class="p4"><span class="s1">宿主：</span></p>
<p class="p4"><span class="s1">犬，キツネ，コヨーテ，タヌキ，イタチ，フェレット，ミンク，スカンク</span></p>
</td>
<td valign="top" class="td23">
<p class="p4"><span class="s1">病理：</span></p>
<p class="p5"><span class="s2">・</span><span class="s1">リンパ系組織と上皮組織に病変</span><span class="s2">。</span></p>
<p class="p4"><span class="s1">・胸腺の萎縮，リンパ球の脱落，</span></p>
<p class="p4"><span class="s1">・間質性およびカタル性肺炎。</span></p>
<p class="p4"><span class="s1">・エオジン好性の細胞質内および核内封入体(膀胱上皮，腎盂，グリア細胞，神経細胞，気管支上皮など)。</span></p>
<p class="p4"><span class="s1">・ウイルスが脳内に侵入してジステンパー脳炎→小脳脱髄病変。（→</span><span class="s4">LFB(ルクソール・ファーストブルー)染色で青</span><span class="s1">）</span></p>
</td>
<td valign="top" class="td24">
<p class="p4"><span class="s1">類症鑑別：</span></p>
</td>
<td valign="top" class="td25">
<p class="p4"><span class="s1">治療：</span></p>
<p class="p4"><span class="s1">二次感染を防ぐための抗生物質投与</span></p>
</td>
</tr>
</tbody>
</table>
<p class="p7"><br></p>
</body>
</html>