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アレルギー - 変更履歴
2026-05-05T12:45:28Z
このウィキのこのページに関する変更履歴
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2014年11月25日 (火) 13:45にGeshtaltによる
2014-11-25T13:45:12Z
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<td colspan='2' style="background-color: white; color:black; text-align: center;">←前の版</td>
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2014-11-25T13:44:36Z
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<body><br />
<p class="p1"><br></p><br />
<table cellspacing="0" cellpadding="0" class="t1"><br />
<tbody><br />
<tr><br />
<td valign="middle" class="td1"><br />
<p class="p2"><span class="s1"><b>発生</b></span></p><br />
</td><br />
<td valign="middle" class="td2"><br />
<p class="p2"><span class="s1"><b>名称</b></span></p><br />
</td><br />
<td valign="middle" class="td3"><br />
<p class="p2"><span class="s1"><b>関与する物質や細胞</b></span></p><br />
</td><br />
<td valign="middle" class="td4"><br />
<p class="p2"><span class="s1"><b>主な疾患</b></span></p><br />
</td><br />
<td valign="middle" class="td5"><br />
<p class="p2"><span class="s1"><b>原因物質</b></span></p><br />
</td><br />
<td valign="middle" class="td6"><br />
<p class="p2"><span class="s1"><b>症状</b></span></p><br />
</td><br />
<td valign="middle" class="td7"><br />
<p class="p2"><span class="s1"><b>メモ</b></span></p><br />
</td><br />
<td valign="middle" class="td8"><br />
<p class="p2"><span class="s1"><b>細胞性</b></span></p><br />
</td><br />
</tr><br />
<tr><br />
<td rowspan="23" valign="middle" class="td9"><br />
<p class="p3"><span class="s1"><b>即時型</b></span></p><br />
</td><br />
<td rowspan="8" valign="middle" class="td10"><br />
<p class="p4"><span class="s1">１型アナフィラキシー反応</span></p><br />
</td><br />
<td rowspan="8" valign="top" class="td11"><br />
<p class="p4"><span class="s1">マストセル</span></p><br />
<p class="p4"><span class="s1">好塩基球へのIgEの結合。</span></p><br />
<p class="p4"><span class="s1">脱顆粒反応</span></p><br />
</td><br />
<td valign="top" class="td12"><br />
<p class="p4"><span class="s1">蕁麻疹</span></p><br />
</td><br />
<td valign="top" class="td13"><br />
<p class="p4"><span class="s1">真菌</span></p><br />
<p class="p4"><span class="s1">塵埃</span></p><br />
</td><br />
<td valign="top" class="td14"><br />
<p class="p4"><span class="s1">皮膚の発赤と腫脹</span></p><br />
<p class="p4"><span class="s1">鼻炎</span></p><br />
<p class="p4"><span class="s1">気管支喘息</span></p><br />
<p class="p4"><span class="s1">呼吸器障害</span></p><br />
<p class="p4"><span class="s1">局所ｱﾅﾌｨﾗｷｼｰ</span></p><br />
<p class="p4"><span class="s1">全身性ショック</span></p><br />
<p class="p4"><span class="s1">皮膚炎</span></p><br />
</td><br />
<td rowspan="8" valign="top" class="td15"><br />
<p class="p4"><span class="s1">IgE産生はTcｺﾝﾄﾛｰﾙ下Th２細胞から産生されるIL４→B細胞のｱｲｿﾀｲﾌﾟｦ変換させる→IgE産生↑</span></p><br />
<p class="p4"><span class="s1">産生されたIgEは局所のマストセルや好塩基球表面の膜表面にあるﾚｾﾌﾟﾀｰ（FcεRI）に結合し脱顆粒する。</span></p><br />
<p class="p4"><span class="s1">（炎症性メディエータ）PG、ﾋｽﾀﾐﾝ､ｾﾛﾄﾆﾝ、ﾍﾊﾟﾘﾝ、ﾛｲｺﾄﾘｴﾝ</span></p><br />
</td><br />
<td rowspan="23" valign="top" class="td16"><br />
<p class="p4"><span class="s1">B細胞</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">花粉アレルギー</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">花粉</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">鼻炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td20"><br />
<p class="p4"><span class="s1">食餌アレルギー</span></p><br />
</td><br />
<td valign="top" class="td21"><br />
<p class="p4"><span class="s1">ジャガイモ、大豆、他にも色々</span></p><br />
</td><br />
<td valign="top" class="td22"><br />
<p class="p4"><span class="s1">気管支喘息</span></p><br />
<p class="p4"><span class="s1">呼吸器障害</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td23"><br />
<p class="p4"><span class="s1">薬物orﾜｸﾁﾝアレルギーｼｮｯｸ</span></p><br />
</td><br />
<td valign="top" class="td24"><br />
<p class="p4"><span class="s1">昆虫毒</span></p><br />
<p class="p4"><span class="s1">ヒナ白痢ﾜｸﾁﾝ</span></p><br />
<p class="p4"><span class="s1">狂犬病ﾜｸﾁﾝ</span></p><br />
</td><br />
<td valign="top" class="td25"><br />
<p class="p4"><span class="s1">局所ｱﾅﾌｨﾗｷｼｰ</span></p><br />
<p class="p4"><span class="s1">全身性ショック</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p4"><span class="s1">寄生虫感染症</span></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p4"><span class="s1">吸虫 線虫</span></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p5"><br></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p4"><span class="s1">アトピー性皮膚炎</span></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p4"><span class="s1">皮膚炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p4"><span class="s1">腸管アレルギー</span></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p5"><br></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p5"><br></p><br />
</td><br />
</tr><br />
<tr><br />
<td rowspan="6" valign="middle" class="td29"><br />
<p class="p4"><span class="s1">２型細胞融解反応</span></p><br />
</td><br />
<td rowspan="6" valign="top" class="td30"><br />
<p class="p4"><span class="s1">補体</span></p><br />
<p class="p4"><span class="s1">FcRを持つ攻撃細胞または補体による細胞溶解。</span></p><br />
<p class="p4"><span class="s1">液性免疫の連鎖による細胞障害。</span></p><br />
<p class="p4"><span class="s1">標的細胞へ抗体が直接付着。</span></p><br />
<p class="p4"><span class="s1">抗体依存性細胞性障害ＡＤＣＣ</span></p><br />
</td><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">自己免疫性皮膚炎</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">皮膚（犬、猫、馬）</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">類天疱瘡</span></p><br />
</td><br />
<td rowspan="6" valign="top" class="td31"><br />
<p class="p4"><span class="s1">生体自身の細胞や組織に結合した抗体が補体系を活性化。抗体依存性の細胞障害反応。</span></p><br />
<p class="p4"><span class="s1">細胞や組織が抗体に直接攻撃される</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">薬剤アレルギー</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">ﾄﾘﾒﾄﾌﾟﾘﾑ ｻﾙﾌｧ剤（犬）</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">溶血性貧血・血小板減少症</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">自己溶血性貧血（ＡＩＨＡ）</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">赤血球・血小板（犬、牛）</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">溶血性貧血</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p4"><span class="s1">橋本病</span></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p4"><span class="s1">甲状腺炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">原虫感染症</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">ﾄﾘﾊﾟﾉｿｰﾏ、ｱﾅﾌﾟﾗｽﾞﾏ（牛）</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">溶血性貧血</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">移植免疫</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">移植組織、臓器</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">移植組織排除</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td rowspan="9" valign="middle" class="td32"><br />
<p class="p4"><span class="s1">３型アレルギー</span></p><br />
<p class="p4"><span class="s1">（抗原抗体複合体）</span></p><br />
</td><br />
<td rowspan="9" valign="top" class="td33"><br />
<p class="p4"><span class="s1">補体</span></p><br />
<p class="p4"><span class="s1">好中球</span></p><br />
<p class="p4"><span class="s1">免疫複合体の形成と局所への沈着。</span></p><br />
<p class="p4"><span class="s1">または好中球、ｍφの集積</span></p><br />
</td><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">薬物アレルギー</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">抗生物質（犬）</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">発熱、貧血、蛋白尿</span></p><br />
</td><br />
<td rowspan="9" valign="top" class="td34"><br />
<p class="p4"><span class="s1">通常ならば速やかに細網系によって流血中から除去されるはずの抗原抗体複合体が局所に沈着して補体系と反応し、ｱﾅﾌｨﾗﾄｷｼﾝを始めとする炎症性メディエータが産生されて炎症が起こる</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">血清病</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">異種血清蛋白</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">アルチュス反応</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">全身性ｴﾘﾃﾏﾄｰﾃﾞｽ</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">核酸 蛋白</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">皮膚発赤 糸球体腎炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">リウマチ性関節炎</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">リウマチ因子</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">慢性関節炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">ＦＩＰ</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">コロナウイルス</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">高γｸﾞﾛﾌﾞﾘﾝ血症</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">ﾐﾝｸｱﾘｭｰｼｬﾝ病</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">ﾊﾟﾙﾎﾞｳｲﾙｽ</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">膜性糸球体腎炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">蕁麻疹型豚丹毒</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">ｴﾘｼﾞﾍﾟﾛｽﾘｯｸｽ</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">蕁麻疹様発赤、関節炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">ﾜｸﾁﾝの副作用</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">口蹄疫</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">血管炎など</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">寄生虫感染症</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">犬糸状虫</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">糸球体腎炎など</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td rowspan="5" valign="middle" class="td35"><br />
<p class="p3"><span class="s1"><b>遅発型</b></span></p><br />
</td><br />
<td rowspan="5" valign="middle" class="td36"><br />
<p class="p4"><span class="s1">４型細胞性免疫</span></p><br />
</td><br />
<td rowspan="5" valign="top" class="td37"><br />
<p class="p4"><span class="s1">感作ﾘﾝﾊﾟ球</span></p><br />
<p class="p4"><span class="s1">ﾘﾝﾎｶｲﾝ</span></p><br />
<p class="p4"><span class="s1">ﾘﾝﾎｶｲﾝによる炎症反応の誘導</span></p><br />
<p class="p4"><span class="s1">ｍφの集積、活性化による組織障害</span></p><br />
</td><br />
<td valign="top" class="td26"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p5"><br></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p5"><br></p><br />
</td><br />
<td rowspan="5" valign="top" class="td38"><br />
<p class="p4"><span class="s1">12時以上かけて発現</span></p><br />
</td><br />
<td rowspan="5" valign="top" class="td39"><br />
<p class="p4"><span class="s1">T細胞</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td23"><br />
<p class="p4"><span class="s1">細菌感染症（皮内反応）</span></p><br />
</td><br />
<td valign="top" class="td24"><br />
<p class="p4"><span class="s1">ブルセラ</span></p><br />
<p class="p4"><span class="s1">抗酸菌など真菌</span></p><br />
<p class="p4"><span class="s1">寄生虫も</span></p><br />
</td><br />
<td valign="top" class="td25"><br />
<p class="p4"><span class="s1">肉芽腫性炎</span></p><br />
<p class="p4"><span class="s1">結核</span></p><br />
<p class="p4"><span class="s1">皮膚に局所の紅斑と硬結</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td20"><br />
<p class="p4"><span class="s1">ウイルス感染症</span></p><br />
</td><br />
<td valign="top" class="td21"><br />
<p class="p4"><span class="s1">ワクシニアウイルス</span></p><br />
<p class="p4"><span class="s1">アレナウイルス</span></p><br />
</td><br />
<td valign="top" class="td22"><br />
<p class="p4"><span class="s1">皮膚炎</span></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td26"><br />
<p class="p4"><span class="s1">ﾜｸﾁﾝの副作用</span></p><br />
</td><br />
<td valign="top" class="td27"><br />
<p class="p4"><span class="s1">狂犬病ﾜｸﾁﾝ</span></p><br />
</td><br />
<td valign="top" class="td28"><br />
<p class="p5"><br></p><br />
</td><br />
</tr><br />
<tr><br />
<td valign="top" class="td17"><br />
<p class="p4"><span class="s1">移植免疫</span></p><br />
</td><br />
<td valign="top" class="td18"><br />
<p class="p4"><span class="s1">狂犬病</span></p><br />
</td><br />
<td valign="top" class="td19"><br />
<p class="p4"><span class="s1">髄膜性脳炎</span></p><br />
</td><br />
</tr><br />
</tbody><br />
</table><br />
<p class="p5"><br></p><br />
</body><br />
</html></div>
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